Forensic Genetic Genealogy
Through efficient stewardship and its unique combined capabilities as both a forensic DNA crime lab and a research and development lab, CHI became the first public forensic laboratory in the U.S. to be accredited for Single Nucleotide Polymorphisms (SNPs) using Massively Parallel Sequencing (MPS) technology. The data generated from this technology is compatible with the public genealogical databases available for law enforcement searches.
Renowned for its scientists’ specialization with degraded evidence, kinship testing, mitochondrial DNA and Y-chromosomal testing, CHI has been rolling out a multi-tiered SNP testing approach that uses multiple technologies to accommodate each sample’s challenges while maximizing the possibility of a successful result.
Eligibility for Forensic Genetic Genealogy (FGG) testing follows the case criteria outlined in the United States Department of Justice Interim Policy for Forensic Genetic Genealogical DNA Analysis and Searching to the extent possible. The DNA extract originating from a suspect or unidentified human remains that was used to develop the autosomal STR profile for CODIS entry must be available for SNP testing. If the DNA extract is not available, a sufficient amount of material from the same sample used for the CODIS entry must be available for re-extraction. The DNA extract will undergo SNP testing using the appropriate technology or technologies and a confidential laboratory report will be issued to your agency that details the testing results, which includes the SNP profile’s eligibility for entry into GEDmatch PRO™. If the results meet the entry requirements set forth by GEDmatch PRO™, a qualified analyst will enter the SNP profile for subsequent searching by a CHI genetic genealogist.
If no investigative leads are generated from the genetic genealogical research after a specified time period, a notification will be issued to the agency stating that no leads have been generated but that the SNP profiles will remain in GEDmatch PRO™ and continue to be searched. If the genetic genealogical research identifies one or more potential candidates, a confidential report will be issued that details the research, identifies the potential candidate(s), and provides additional guidance on next steps.
CHI can offer investigative consultation to your agency which may include information regarding the location of a reference tester and guidance on how to collect and submit samples for comparison to the original testing laboratory for confirmation with the autosomal STR CODIS entry. CHI will remove the SNP profile from GEDmatch PRO™ if informed by the agency that the identity has been confirmed.
To submit your case for consideration, please complete CHI’s Forensic Genetic Genealogy Evaluation Form and Attestation and email these together with the investigative narrative and serology and/or DNA report (if available), to FGGUnit@unthealth.edu. After review, your agency will be contacted for any necessary follow-up. If approved, packaging and shipment instructions for subsequent submission will be provided, as needed.